Spleen and PP

Speen

• The spleen is the major site of adpative immune responses to blood-borne antigens. The spleen ingest 0psonized antigens and daaged red blood cells and contains lymphocytes and lymphoid follicles where B cells are activated (educaton)

PP (Peyers patch)

• Organized lympohoid tissue in the lamina propria of the samll intestine in which immune responses to ingested antigens may be initiated. Peyers patches are composed mostly of B cells, with smaller numbers of T cells and accessory cells, all arranged in follicles similar to those found in lymph nodes, oftern with germinal centers.